Detalhe da pesquisa
1.
Human Epistatic Interaction Controls IL7R Splicing and Increases Multiple Sclerosis Risk.
Cell
; 169(1): 72-84.e13, 2017 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28340352
2.
The Awesome Power of Human Genetics of Infectious Disease.
Annu Rev Genet
; 56: 41-62, 2022 11 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35697043
3.
Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections.
Cell
; 148(3): 434-46, 2012 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22304914
4.
Targeting senescent hepatocytes using the thrombomodulin-PAR1 inhibitor vorapaxar ameliorates NAFLD progression.
Hepatology
; 78(4): 1209-1222, 2023 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37036206
5.
ARHGEF26 enhances Salmonella invasion and inflammation in cells and mice.
PLoS Pathog
; 17(7): e1009713, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34242364
6.
Human genetic variation in VAC14 regulates Salmonella invasion and typhoid fever through modulation of cholesterol.
Proc Natl Acad Sci U S A
; 114(37): E7746-E7755, 2017 09 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28827342
7.
Methylthioadenosine Suppresses Salmonella Virulence.
Infect Immun
; 86(9)2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29866910
8.
Multiple Surface Regions on the Niemann-Pick C2 Protein Facilitate Intracellular Cholesterol Transport.
J Biol Chem
; 290(45): 27321-27331, 2015 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26296895
9.
Calcineurin orchestrates dimorphic transitions, antifungal drug responses and host-pathogen interactions of the pathogenic mucoralean fungus Mucor circinelloides.
Mol Microbiol
; 97(5): 844-65, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26010100
10.
Reply to Gilchrist et al.: Possible roles for VAC14 in multiple infectious diseases.
Proc Natl Acad Sci U S A
; 115(16): E3604-E3605, 2018 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29588421
11.
Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death.
Proc Natl Acad Sci U S A
; 109(35): E2343-52, 2012 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22837397
12.
Nuclear factor kappa B-dependent persistence of Salmonella Typhi and Paratyphi in human macrophages.
mBio
; 15(4): e0045424, 2024 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38497655
13.
A single amino acid in the Salmonella effector SarA/SteE triggers supraphysiological activation of STAT3 for anti-inflammatory target gene expression.
bioRxiv
; 2024 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38405869
14.
The Legacy of Past Pandemics: Common Human Mutations That Protect against Infectious Disease.
PLoS Pathog
; 12(7): e1005680, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27442518
15.
Human variation impacting MCOLN2 restricts Salmonella Typhi replication by magnesium deprivation.
Cell Genom
; 3(5): 100290, 2023 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37228749
16.
The RNA helicase DDX39B activates FOXP3 RNA splicing to control T regulatory cell fate.
Elife
; 122023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37261960
17.
A genome-wide in vitro bacterial-infection screen reveals human variation in the host response associated with inflammatory disease.
Am J Hum Genet
; 85(2): 214-27, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19664744
18.
Integration of the Salmonella Typhimurium Methylome and Transcriptome Reveals That DNA Methylation and Transcriptional Regulation Are Largely Decoupled under Virulence-Related Conditions.
mBio
; 13(3): e0346421, 2022 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35658533
19.
Human genetic diversity regulating the TLR10/TLR1/TLR6 locus confers increased cytokines in response to Chlamydia trachomatis.
HGG Adv
; 3(1): 100071, 2022 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35047856
20.
The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction.
Cell Host Microbe
; 30(12): 1671-1684.e9, 2022 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36084633